The skin-whitening products are among the most popular products in dermatology and dermatology-related niche.
But a new study from the University of Pennsylvania School of Medicine shows that a similar product is equally effective as an all-natural product in reducing skin aging and improving the appearance of skin.
“Biotique is one of the most widely sold whitening products in the U.S.,” said lead author Dr. Matthew G. Fenton, MD, associate professor of dermatology at the University School of Dermatology.
“It’s also one of our top-selling whitening and moisturizing products in general, and it’s a good candidate for an antioxidant-rich product that also helps improve the appearance.”
The study looked at the effects of two different biotiques whitening serums in subjects with different skin types and different age ranges.
A sample of the Biotiques Whitening serum (BiTQ-002) contained a blend of vitamins A, B6, B12, and beta-carotene (BC) and a mixture of antioxidants (B1, B2, B3, and B6).
The B6-rich biotircine, or a blend, was formulated to contain both vitamin B6 and vitamin A. The BiTQ moisturizing serum (BQM-003) contained vitamin E and vitamin E fatty acid, and the B12-rich BQM serum contained vitamin B12 and beta carotene.
The serum had a pH of 6.5 and had no preservatives.
The subjects also had regular visits to the dermatologist to see how they looked after the serum was applied.
“We knew there was an effective treatment, and we didn’t expect it to be as effective as the BiTiq moisturizing solution,” said Fenton.
“So we tried to get as many subjects as we could, so that we could evaluate the effect of the biotiquing serum and its antioxidant-packed ingredients.”
A second study tested the BiOTQ-003 and BQB-003 whitening formulas in patients who had skin types ranging from medium to dark-skinned and had been diagnosed with skin aging or acne.
Both products were given as injections in the form of capsules or powder.
The BQC-003 contained both vitamin C and vitamin C-rich vitamin E, while the BiTC-003 was formulated for a mix of vitamin C, vitamin E. The skin whitening agents were also given to patients with mild to moderate acne, skin with oily skin, and mild to medium skin aging.
The biotouring agents had a combined antioxidant capacity of 100 percent (BAC) compared with a BAC of 0 percent.
Both formulations had the same pH of 5.8, had no added preservatives, and were free of fragrance.
In a third study, the researchers gave the BiTS-003 serum to subjects with moderate to severe acne and found that the BQS-003 had similar antioxidant properties to the BiRT-003, with a similar pH of 3.8.
The researchers also tested the biotin-rich serum for its ability to promote skin healing and reduce inflammation.
The two biotin formulations had similar BACs (5.6 percent and 3.4 percent) and BAC-dependent levels of vitamin E (2.7 percent and 1.4).
The biotin mixture had a higher antioxidant capacity than the BTS- and BiTCs-003s (20.4 and 17.4 mg/ml, respectively).
The researchers did not see any significant differences in skin appearance between the two products.
“This study shows that skin whiteners can have similar antioxidant and anti-inflammatory effects, even with the same active ingredient,” said Dr. David L. Pappas, MD.
“And we are looking forward to further evaluating the biOTQ and BiTS whitening solutions in more clinical studies in future.”
The researchers will also test the BiET-003 with the BiCT-003 in the skin-conditioning study.
“The BiOTIQ is a natural and inexpensive way to whitening your skin and moisturize the skin,” said Pappachas.
“But in the meantime, it’s great to know that there is a biotasking solution out there that works well and is very inexpensive.”
Follow Stephanie Pappaski on Twitter @sipappaskis and Facebook.